...Are you SERIOUS? I don't have experience with every game there, but...what the hell? Mass Effect 2 is COMPLETELY different from 1, with more improved shooting, leveling up changed, the powers at your disposal were all heavily tweaked, getting rid of loot, etc. Mass Effect 3 isn't even out, so I have no idea why you mentioned that. GTA3 is a huge departure from the other GTA games. Oblivion isn't even the third ES game. MGS3 was a big departure from the other 2. Bioshock, again, doesn't have a third game out yet, and Infinite looks completely different. All three Killzone games are pretty different. Assassin's Creed has been changed a lot in each iteration. Fallout 3 is a HUGE departure, which is common knowledge. Saints Row 3 isn't out. Diablo 3 isn't out.
I have no idea what you were thinking with that list of random popular games, because many of them have done exactly what you said they haven't and outright aren't even out to judge.