After playing the game a metric ass-ton, as soon as a level cap mod comes out, or a very balanced damage mod, I'll be using it. With all the talk of the improved shooting mechanics (it is better), things really start to get wonky level 50+, especially in the areas (late game) where you are fighting large groups of enemies. They hardly damage you at this point, but you also barely damage them, even with maxed out weapon perks and fully upgraded weapons. My one character is over level 70 (damn idiot perk), and I can stand in front of certain same level enemies with an explosive shotgun and just shoot and shoot and shoot. Incredibly boring, and that's on very hard. No way I'd play on survival and nerf my damage even more.
Ninja sneak attacks can waste everything, but why play every character the same way?